Oxandrolone is an oral anabolic steroid derived from dihydrotestosterone (DHT). It was specifically engineered to offer a strong separation between anabolic and androgenic effects, while exhibiting no significant estrogenic or progestogenic activity. Compared to other oral steroids, oxandrolone is considered relatively mild, both in terms of side effects and overall hormonal disruption.
The compound was developed to promote strength and lean muscle gains without the common drawbacks associated with stronger androgens. In anabolic assays, oxandrolone has demonstrated up to six times the anabolic activity of testosterone on a milligram-for-milligram basis, with substantially reduced androgenicity.
This profile makes oxandrolone a popular choice among cutting-phase bodybuilders and competitive athletes—particularly those involved in speed or anaerobic sports—where lean mass gains without fat or water retention are highly desirable.
Structurally, oxandrolone features a unique modification at the second carbon atom: a carbon is replaced by an oxygen atom, which gives the compound its “ox” prefix. This seemingly small structural change is believed to play a major role in enhancing its anabolic potency compared to its parent hormone, dihydrotestosterone.
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